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报告题目:
Functional DNA Sensors based on Catalytic Beacon and Directed Assembly of Nanomaterials
 报告人:
Yi Lu
Professor
Department of Chemistry
University of Illinois at Urbana-Champaign
报告时间:
2008-06-16 14:00
报告地点:
生命科学馆143会议室
主办单位:
清华大学化学系
  简介:

简介:
Prof. Yi Lu is a Professor of Chemistry in Department of Chemistry, University of Illinois at Urbana-Champaign (UIUC) since 2004. He received his B.S. in Chemistry at Beijing University (PKU) in 1986, and then Ph.D. in Chemistry at University of California, Los Angeles (UCLA) in 1992. After a two years’ postdoctoral research fellow at California Institute of Technology, he joined UIUC as an Assistant Professor of Chemistry in 1994. Later, he was promoted as Associate Professor of Chemistry and Professor of Chemistry at UIUC in 2000 and 2004, respectively.
Prof. Lu’s research interests include “Biosynthetic Inorganic Chemistry”, “New Metallo-DNAzymes” and “Employing Principles from Biology to Nanomaterials Synthesis”.

Selected recent publications of Prof. Lu:

1. Sarangi, R.; Gorelsky, S. I.; Basumallick, L.; Hwang, H. J.; Pratt, R. C.; Stack, T. D. P.; Lu, Y.; Hodgson, K. O.; Hedman, B.; Solomon, E. I., “Spectroscopic and Density Functional Theory Studies of the Blue-Copper Site in M121SeM and C112SeC Azurin: Cu-Se Versus Cu-S Bonding”, J. Am. Chem. Soc. 130, 3866-3877 (2008).

2. Yi Lu and Juewen Liu, “Nanomaterials Inspired by Biology: Dynamic Assembly of Error-Free Nanomaterials in Response to Multiple Chemical Stimuli,”, Acc. Chem. Res. 40, 315-323 (2007)

3. Juewen Liu, Andrea K. Brown, Xiangli Meng, Donald M. Cropek, Jonathan D. Istok, David B. Watson, and Yi Lu, “A catalytic beacon sensor for uranium with parts-per-trillion sensitivity and million-fold selectivity,”, Proc. Natl. Acad. Sci. USA, 104, 2056-2061 (2007)

4. Hee-Kyung Kim, Ivan Rasnik, Juewen Liu Taekjip Ha, and Yi Lu, “Dissecting metal ion dependent folding and catalysis of a single DNAzyme”, Nature Chem. Biol. 3, 763-768 (2007)

5. Jung Heon Lee, Daryl P. Wernette, Mehmet V. Yigit, Juewen Liu, Zidong Wang, and Yi Lu, “Site-Specific Control of Distances between Gold Nanoparticles using Phosphorothioate Anchors on DNA and a Short Bifunctional Molecular Fastener”, Angew. Chem., Int. Ed. 46, 9006-9010 (2007)

6. Juewen Liu and Yi Lu, “A DNAzyme Catalytic Beacon Sensor for Paramagnetic Cu2+ Ions in Aqueous Solution with High Sensitivity and Selectivity”, J. Am. Chem. Soc. 129, 9838-9839 (2007)

7. Juewen Liu and Yi Lu, “Preparation of aptamer-linked gold nanoparticle purple aggregates for colorimetric sensing of analytes”, Nature Protocol, 1, 246-252 (2006)

8. Kashan Shaikh, Kee Suk Ryu, Edgar Doluch, Jwa-Min Nam, Juewen Liu, C. Shad Thaxton, Thomas Chiesl, Annelise Barron, Yi Liu, Chad Mirkin, Chang Liu, "A Modular Microfluidic Architecture for Intergrated Biochemical Analysis", Proc. Natl. Acad. Sci., 102, 9745-9750 (2005)

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