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报告题目:
Bio-inspired Multi-scale Pores and Channels
 报告人:
侯旭博士
Harvard University
Wyss Institute for Biologically Inspired Engineering
School of Engineering and Applied Sciences
报告时间:
2015-06-25 10:00
报告地点:
何添楼406会议室
主办单位:
化学系刘冬生课题组
  简介:

报告摘要:

Life through millions of years of evolution has almost completed all the process of intelligent control. Learning from nature is the eternal theme of the development of novel smart materials and new intelligent systems. Here I will introduce my research progress on bio-inspired multi-scale pore and channel systems and their potential application for the real world. For example, typically ion channels, biological nanochannel, play a very important role in the cellular basic molecular biological processes. The components of ion channels are asymmetrically distributed between membrane surfaces. Inspired by these channels, the generation of biomimetic smart nanochannels is a delightfully varied scientific research field. It also boosts the study of design and development of new biomimetic channels by use of different shapes of the channels, different stimuli-responsive molecules and different symmetric/asymmetric chemical modification methods. Another example, as gatekeepers between complex environments, micro/nanopores in living organisms have evolved to extract fluids, vapors, and solids from soil, air, and ocean, sort them among internal compartments to control buoyancy, pressure, body patterning, sensing and metabolic cascades, and eliminate wastes, toxins, and pathogens. This ability to coordinate multi-phase transport – responsively and without clogging – has inspired interest in designing gated pores for uses as diverse as oil, gas, wastewater, and blood processing, 3D-printing of stem cells, refreshable tactile displays, soft-robotic hands, liquid and aerosol therapies, and lab-on-chip microfluidic systems. However, despite progress in programming specific gating and transport behaviors, a single system capable of complex multiphase selectivity and control has remained a distant prospect, and fouling is nearly inevitable. Here, I introduce a new, unified gating concept that integrates responsive pore opening/closing with broad multi-phase discrimination and anti-fouling behavior. The gating strategy can be applied to a variety of pore structures, material chemistries, and micro/macroscale systems, suggesting opportunities for complex sorting in environmental, fuel, biomedical, microfluidics, 3D-printing, and other applications.

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