New Developments in Stereoselective Indium-Mediated Reactions
报告人:
Professor Gregory R. Cook
Department of Chemistry and Molecular Biology North Dakota State University, USA
报告时间:
2006-03-10 10:00
报告地点:
何添楼406会议室
主办单位:
清华大学化学系
简介:
• Research Interests • We are interested in developing new selective reactions for application toward the synthesis of natural and unnatural compounds of biological and material interest. Our synthetic methodology is directed toward the stereoselective allylation of carbonyls and imines mediated by indium metal. These new carbon-carbon bond forming processes produce chiral alcohols and amines found in a variety of target molecules. Our medicinal chemistry interests lie in the development of new small molecule inhibitors for matrix metalloproteases (MMPs) and histone deacetylases (HDACs) for the treatment of cancer, lupus and other autoimmune diseases. We are also pursuing the preparation of conjugated polymers for new electrically conducting coatings.
