简介: |
Continuous monitoring of blood pressure, an essential measure of health status, typically requires complex, costly, and invasive techniques that can expose patients to risks of complications. Continuous, cuffless, and noninvasive blood pressure monitoring methods that correlate measured pulse wave velocity (PWV) to the blood pressure via the Moens−Korteweg (MK) and Hughes Equations, offer promising alternatives. The MK Equation, however, involves two assumptions that do not hold for human arteries, and the Hughes Equation is empirical, without any theoretical basis. The results presented here establish a relation between the blood pressure P and PWV that does not rely on the Hughes Equation nor on the assumptions used in the MK Equation. This relation degenerates to the MK Equation under extremely low blood pressures, and it accurately captures the results of in vitro experiments using artificial blood vessels at comparatively high pressures. For human arteries, which are well characterized by the Fung hyperelastic model, a simple formula between P and PWV is established within the range of human blood pressures. This formula is validated by literature data as well as by experiments on human subjects, with applicability in the determination of blood pressure from PWV in continuous, cuffless, and noninvasive blood pressure monitoring systems.
个人简历: 黄永刚,美国西北大学冠名讲座教授,美国国家工程院院士,欧洲科学院院士和中国科学院外籍院士。1984年获北京大学学士学位,1990年获哈佛大学博士学位。 主要研究领域是材料和电子器件的力学行为,他和合作者共同开创了可延展无机电子器件领域。发表500余篇SCI论文,被引用将近六万次。近六年曾获美国机械工程师协会2013年德鲁克奖章(Drucker Medal,该协会力学类三大奖之一)和2016年纳达尔奖章(Nadai Medal,该协会材料类最高奖),国际工程科学协会的2017年普拉格奖章(Prager Medal,该协会最高奖),美国土木工程师协会2018年巴赞特奖章(Bazant Medal,该协会破坏损失类唯一奖)。他还获得过多项亚利桑那大学,伊利诺伊大学和西北大学的教学和本科生指导奖。
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