The inflammatory response contributes to the development and progression of cancer. Recent data have shown that many cancers arise from chronic inflammation，including extrinsic factors, such as infection, autoimmunity, tobacco smoke and intrinsic factors such as oncogene activation. Although inflammation do not always cause cancers, inflammatory responses play pivotal roles at different stages of tumor progression, including initiation, promotion, invasion, and metastasis. Chronic inflammatory response produces cytokines, growth factors that may promote cell proliferation and suppress apoptosis, which contributes to an increased risk of cancer. Clinical and epidemiological studies have suggested a strong association between inflammation and different types of cancer. However, the precise mechanistic linkage between inflammation and tumorigensis are just beginning to be understood. Uncover the roles of key proteins and molecular events that governing the onset and progression of inflammation induced cancer would provide new insights into the origin and treatment of human cancers.

Host: Prof. Yigong Shi

Date: 4:00PM-5:00PM, Nov. 22 (Thursday)

Venue: 143,NewBiology Building