报告人简历:
Ronald Breslow did his Ph.D. research with Prof. R.B. Woodward at Harvard University. He then went to Cambridge as a postdoctoral fellow with Lord Tod. He went to Columbia University in 1956, where he is now the Samuel Latham Mitchill Professor of Chemistry and one of twelve University Professors.
Prof. Breslow's research interests can be described generally as involving the design and synthesis of new molecules with interesting properties, and the study of these properties. His work establishing the phenomenon of anti-aromaticity has involved the synthesis of novel molecules and the chemical mechanism used by vitamin B-1 in biochemical reactions. His major emphasis in recent years has been on the synthesis and study of molecules that imitate enzymatic reactions. This work has included the development of remote functionalization reactions and the development of artificial enzymes. Recently he has developed a new group of cytodifferentiating agents with potential use in cancer chemotherapy. |