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报告题目:
Modeling Biological Systems from Protein Folding to Cell Signaling
 报告人:
Hong Qian(钱洪教授)
Department of Applied Mathematics, University of Washington, Seattle
报告时间:
2005-07-11 15:30
报告地点:
高等研究中心1221会议室
主办单位:
清华大学周培源应用数学研究中心
  简介:

Hong Qian’s biography: 

 

Education & Training:

1992-1994 Postdoctoral Fellow, California Institute of Technology, Pasadena.

Mathematical biology and neural computation (with J.J. Hopfield)

1990-1992 Postdoctoral Fellow, University of Oregon, Eugene.

Biophysical chemistry of peptides, proteins, and DNA (with J.A. Schellman)

1983-1989 Ph.D., Washington University, St. Louis. Biochemistry and Biophysics.

Dissertation: Biophysical characterization of biopolymer solutions and gels by fluorescence

fluctuation studies (with E.L. Elson)

1978-1982 B.A., Peking University, Beijing. Astrophysics.

Thesis: On the effect of finite z-distributions in the density wave theory of spiral structures of

galaxies (with Z.Y. Yue)

 

Professional Experience:

2003- Associate Professor of Applied Mathematics, University of Washington.

2003- Adjunct Associate Professor, Bioengineering, University of Washington.

1997-2003 Assistant Professor of Applied Mathematics, University of Washington.

1997-2003 Adjunct Assistant Professor, Bioengineering, University of Washington.

1997- Associate Director, National Simulation Resource, Univeresity of Washington.

1994-1997 Adjunct Assistant Professor of Biomathematics, UCLA School of Medicine.

 

Reasearch Interest:

(1) Mathematical Theory of Nonlinear DNA Elasticity. Both deterministic and stochastic approaches will be employed.

(2) Mathematical Theory of Ionic Distribution around Cylindrical Molecules and Its Applications to DNA. ODE and its asymptotic analysis, numerical investigation, and Painleve equation.

(3) Mathematical Foundation of Fluorescence Correlation Spectroscopy and Its Related Methods. Including high-order time correlation function and generalization of Green-Kubo formulae.

(4) Protein Folding and Its Related Mathematical Problems. Kinetics in energy landscape, dimension reduction and simplex search, and relation to mutual information.

(5) Fluctuating Nonlinear Biochemical Reactions and Stochastic Resonance. Birth-death processes and Brownian motion, nonlinear oscillation, and phase space analysis: developing a stochastic version of the Wymann-DiCera kinetic network (hypercycle) and show its nonlinear stochastic behavior as well as SR.

(6) Stochastic Macromolecular Mechanics, Nonequilibrium Thermodynamics, and Their Applications. Brownian motion, large deviation theory, and nonlinear diffusion equation.

(7) An Algebreic-Topological Approach to Irreversible Markov Processes. Graph and network theory, asymmetric linear operator and its eigenvalues, non-normal matrix, and Markov processes.

 

联系人:唐 琳

  话:62797063

 

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