摘要：Despite the complex environment in and outside of a cell, the underlying biomolecular networks carry out various cellular functions reliably. How is the stability of a cell state achieved? How can a biological pathway take the cell from one state to another reliably? Here we address these questions by studying the network regulating the cell-cycle of the budding yeast. With the use of different dynamic models such as Boolean network, stochastic network and ordinary differential equations, we demonstrate that this network is extremely stable and robust for its function. The stationary state of the cell corresponds to a global attractor of the dynamics, the biological pathway of the cell-cycle sequence, which is a particular trajectory in the state space, is a globally stable and attracting trajectory of the dynamics. Then we will report our dynamic study of mating pathway of the budding yeast, focusing on its signal transduction pathway.

个人简历：欧阳颀教授，1983年获清华大学物理化学专业理学学士，1989年获法国波尔多第一大学物理化学博士学位；1989-1995年美国德州大学奥斯丁分校博士后、资深研究员；1995-1996年法国尼斯非线性中心客座研究员；1996-1998年美国NEC研究所研究员。1998年北京大学教授。北京大学物理学院长江特聘教授（1998-2004），基金委杰出青年基金获得者（1998-2002），基金委创新团队负责人（2007-2010）。现任北京大学物理学院凝聚态所所长，北京大学前沿交叉研究院理论生物中心副主任，国家介观物理实验室副主任。

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