Abstract:
Developing elegant hybrid systems of biological molecules on two-dimensional nanomaterials is a key in creating novel bio-nanoelectronic devices. Biomolecules self-assembling into ordered structures on these nanomaterials offer a novel bottom-up approach, where organized supramolecular architectures spatially govern the electronics of nanomaterials. Despite the enormous potential in bridging nano- and bio-worlds at the molecular scale, no work has yet realized a way to control electronic properties of nanomaterials by the biomolecular structures. Our research target is the control of the interface between biotechnology and nanotechnology. In this work, we employ solid binding peptides or artificially-designed peptides which have specific binding affinities to solid surfaces and an ability to form peptide nanostructures on atomically flat surfaces [1-3]. These peptides self-assemble monolayer-thick long-range ordered nanostructures on surfaces of single-layer graphene, and on other two-dimensional materials. We observed that self-assembled peptides on a single layer graphene modify its conductivity depending on their assembled structures.
[1] C. R. So, Y. Hayamizu, H. Yazici, C. Gresswell, D. Khatayevich, C. Tamerler, and M. Sarikaya, “Controlling Self Assembly of Engineered Peptides on Graphite by Rational Mutation,” ACS Nano, 6 (2) 1648-1656 (2012)
[2] T. R. Page, Y. Hayamizu, C. R. So, and M. Sarikaya, "Electrical Detection of Biomolecular Adsorption on Sprayed Graphene Sheets,” Biosens. Bioelectron., 33 (1) 304-308 (2012)
[3] D. Khatayevich, C. R. So, Y. Hayamizu, Carolyn Gresswell, and Mehmet Sarikaya, "Controlling the Surface Chemistry of Graphite by Engineered Self-Assembled Peptides" Langmuir, 28 8589 (2012)

CV
2005:          Ph.D., Physics department, University of Tokyo
2005-2008: Post-Doctoral Researcher, AIST, Japan
2008-2009: Post-Doctoral Researcher, University of Tokyo, Japan
2009-2012: Post-Doctoral Researcher, University ofWashington, USA
2012-present: Associate Professor, Tokyo-Tech, JAPAN
http://www.op.titech.ac.jp/lab/hayamizu/index_e.html
E-mail: hayamizu.y.aa@m.titech.ac.jp