Abstract: Feedback modules, which appear ubiquitously in biological regulations, are often subject to disturbances from the input, leading to fluctuations in the output. We have identified a critical quantity: the signed activation time that dictates the noise attenuation capability in feedback systems.
Our findings suggest that the inverse relationship between the noise amplification rate and the signed activation time could be a general principle for many biological systems regardless of specific regulations or feedback loops.
报告人简介: 北京大学学士学位(2001), 2008 年在 Rutgers University 获得博士学位, 现在为加州大学 Irvine 分校访问助理教授. 从事系统生物学方面的研究工作。 |
