Research Interests:
1.Development of innovative synthetic methods
2. Synthetic tactics for the rapid construction of architecturally complex natural and unnatural products
3. Novel bioorganic/medicinal chemistry programs

Recent publications:
1. A. B. Smith, III, A. T. Hoye, D. Martinez-Solorio, W.-S. Kim and R. Tong. Unification of Anion Relay
Chemistry (ARC) with the Takeda and Hiyama Cross-Coupling Reactions: Identification of an Effective Silicon-Based Transfer Agent. J. Am. Chem. Soc. 2012, 134, 4533-4536.
2. G. L. Adams, P. J. Carroll and A. B. Smith, III. Total Synthesis of (+)-Scholarisine A. J. Am. Chem. Soc. 2012, 134, 4037-4040.
3. Q. Xu, K.-C. Huang, K. TenDyke, J. Marsha, J. Liu, D. Qiu, B. Littlefield, K. Nomoto, O. Atasoylu, C. A. Risatti, J. B. Sperry and A. B. Smith, III. In Vitro and In Vivo Anti-Cancer Activity of (+)-Spongistatin 1. Anticancer Res. 2011, 31, 2773-2779.
4. A. B. Smith, III, O. Atasoylu, C. Risatti, C. S. Bennett, J. Liu, H. Cheng, K. TenDyke, Q. Xu. Design,
Synthesis and Biological Evaluation of Diminutive Forms of (+)-Spongistatin I: Lessons Learned. J. Am. Chem. Soc. 2011, 133, 14042-14053.