简介: |
Abstract
With the optimized Ag nanorod array (AgNR) SERS substrates, we show that SERS is able to detect trace amount of virus, bacteria, microRNAs, or other chemical and biological molecules related to diseases. The SERS method can distinguish different viruses/bacteria and virus/bacteria strains, suggesting that this technology can be applied to detect genetically modified viruses.Our experiments demonstrate that SERS can detect and distinguish different rotaviruses from real clinic samples. In the meantime, AgNR based SERS is able to tell the difference between the antibiotic resistant and non-resistant bacteria. Thus, SERS can be used to detect food safety related substances such as foodborne pathogens, toxins, pesticides, antibiotics, and adulteration agents. Besides differentiating different types and serotypes of bacteria, SERS can be used to discriminate mycotoxins of similar chemical structures, such as aflatoxins, with the help of chemometric analysis of the SERS spectra. Pesticides from real food samples, such as tea, can be identified using this method with the same multivariate statistical analysis. All the development has demonstrated that AgNR SERS substrates could play an important role for practical sensing applications in future biomedical applications.
个人简历：
Dr. Yiping Zhao received his B.S. degree in Electronics from PekingUniversity in 1991; and MS degree in condensed matter physics fromInstitute of Semiconductors, Chinese Academy of Sciences in 1994. Hecompleted his Ph.D. degree in Physics at Rensselaer Polytechnic Institutein 1999. He is currently a Professor at the Department of Physics andAstronomy in University of Georgia. His major research interests arenanostructures and thin films fabrication and characterization, chemicaland biological sensors, hydrogen storage materials, novel photocatalysts,biomaterials, and nanomotors.
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