报告题目: |
Functional Nanofiber Matrices for Stem Cell Engineering and Tissue Regeneration |
报告人: |
Hai-Quan Mao |
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Ph.D.
Associated Professor
Department of Materials Science and Engineering
Translational Tissue Engineering Center,
Whitaker Biomedical Engineering Institute
Johns Hopkins School of Medicine, USA
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报告时间: |
2011-07-01 10:00 |
报告地点: |
医学院B321 |
主办单位: |
医学院 |
简介: |
It has long been recognized that the in vivo extracellular matrices, e.g. basal lamina, exhibit characteristic micro to nanoscale fibrous topography. Ample experimental evidence demonstrates that artificial matrix topographical features significantly influence the adhesion, survival, proliferation and differentiation of stem cells. Electrospun fiber matrices have been explored as artificial substrates for stem cell culture to regulate stem cell adhesion, proliferation and differentiation in a cell-type specific manner. In this seminar, several case studies will be presented to demonstrate the effect of functional nanofiber matrices on hematopoietic stem cell expansion, neural stem cell differentiation and on the migration, maturation and functional maintenance of tissue cell types. The potential of these nanofiber matrices for regenerative medicine will be discussed. |
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