简介: |
摘要：
Microtubules (MTs) are the most rigid filaments of eukaryotic cytoskeleton and largely responsible for shape and mechanical rigidity of cells. In view of the fact that microtubules exhibit strong anisotropic elastic properties, an orthotropic elastic shell model for microtubules is developed to study buckling behavior of microtubules. The predicted critical pressure is found to agree well with recent unexplained experimental data on pressure-induced buckling of microtubules which are lower than that predicted by isotropic shell model by four orders of magnitude. General buckling behavior of microtubules under axial compression or radial pressure is studied. The results show that isotropic shell model greatly overestimates the bucking loads of microtubules, except column-like axially compressed buckling of long microtubules (of length-to-diameter ratio larger than, say 150). In particular, the present results also offer a plausible explanation for the length-dependency of flexibility of microtubules reported in the literature.
简历： 茹重庆，1954年出生于重庆。1982年本科毕业于兰州大学，1988年在北京大学力学系获博士学位。2004年开始担任加拿大阿尔伯塔大学机械系的正教授，他在固体力学领域的多个重要领域，如碳纳米管力学、微纳米尺度固体力学、微纳米尺度生物力学、固体力学中的多尺度模拟、碳纳米管复合材料等有着深入的研究，取得了一系列有重要影响力的科研成果。其中，从2000年到2005年12月，茹教授在碳纳米管方面的文章已被国际期刊引用超过400次。 |
