摘要:
Biological Network Engineering in Synthetic biology
Qi Ouyang
Center for Quantitative Biology and School of Physics, Peking University
100871, China
Synthetic biology is a new branch of interdisciplinary science that has been developed in recent years for the application of biological technology. The main purpose of synthetic biology is to develop basic biological functional modules, and through rational design, develop man-made biological systems that have predicted useful functions, including calculations. In this talk, I will discuss two principles in rational design of functional biological circuits: the forward engineering design and the reverse engineering design. I will use a few synthetic biology researches that conducted in my laboratory at Peking University to illustrate the above principles: Synthesis of “Pavlov bacteria”; and synthesis a cell which has a semi-log dose-response to the environment. These works demonstrate the potential application of network engineering in synthetic biology.
欧阳颀教授简介:
欧阳颀教授,男,博士,中国科学院院士,北京大学物理学院长江学者特聘教授,国家杰出青年基金获得者,北京大学物理学院凝聚态所所长,国家介观物理重点实验室副主任,北京大学理论生物学中心副主任。 1982年于清华大学化学与化学工程系获学士学位;1987年于法国波尔多第一大学获硕士学位(三阶段博士);1989年于法国波尔多第一大学获博士学位。1989年到1995年在美国得克萨斯州立大学奥斯汀分校非线性动力学中心做博士后研究员及研究员。1995年到1996年在法国尼斯非线性中心做客座研究员。1996年到1998年在美国日本电气公司研究中心做研究科学家。1998年受聘于北京大学物理学院,任教授。同年被评为第一届长江特聘教授。目前主要研究领域为非线性动力学、斑图动力学、生物物理、系统生物学与合成生物学。 |